2012年2月15日星期三

The people who did not wake up frequently during

A new study, which will be presented at the American Academy of Neurology's 64th Annual Meeting in New Orleans, April 21st to April 28th, reveals that the amount Burberry ties of shut-eye people sleep may later affect their memory's function and the risk of Alzheimer's. Study author, Yo-El Ju, M.D., from the University School of Medicine, St. Louis, and a member of the American Academy of Neurology, explained: "Disrupted sleep appears to be associated with the build-up of amyloid plaques, a hallmark marker of Alzheimer's disease, in the brains of people without memory problems. Further research is needed to determine why this is happening and whether sleep changes may predict cognitive decline." To determine their findings, the authors analyzed the sleep patterns of 100 patients, aged between 45 and 80, who did not show any signs of dementia. 50% of these patients had a history of Alzheimer's disease in their families, the other 50% did not have any history of Alzheimer's disease in their families. The researchers placed a monitor on the patients in order to record their sleep for 2 weeks. They were also asked to record their sleeping habits and fill out surveys. The study determined that 25% of the patients showed signs of amyloid plaques, which predict Alzheimer's in the future, and can be seen many years before they are diagnosed with the progressive disease. The mean amount of time the participants slept during the study was 8 hours. However, the average was reduced - to 6.5 hours - because of disruptions in their sleep throughout the night. The people who did not wake up frequently during the night were 5 times less likely to possess the amyloid plaque build-up than the people who did not sleep well. The people who did not sleep well were also found to have a greater chance of having the "markers" of early stage Alzheimer's. This means, those who spent 85% of their time in bed, sleeping soundly, have a lower risk of Alzheimer's than those who spent 85% of the time in bed tossing and turning. "The association between disrupted sleep and amyloid plaques is intriguing, but the information from this study can't determine a cause-effect relationship or the direction of this relationship. We need longer-term studies, following individuals' sleep over years, to determine whether disrupted sleep leads to amyloid plaques, or whether brain changes in early Alzheimer's disease lead to changes in sleep. Our study lays the groundwork for investigating Burberry belts whether manipulating sleep is a possible strategy in the prevention or slowing of Alzheimer's disease" Children's Hospital of Philadelphia (CHOP) has apologized to the parents of Amelia Rivera, a disabled three-year-old girl who, according to her parents, was initially denied a chance at a kidney transplant because she is "mentally retarded." In a statement released jointly with Joe and Chrissy Rivera today, a hospital official also promised to review the way the hospital handles such cases. And Amelia's possible transplant is now under consideration, as her parents have previously reported. "As an organization, we regret that we communicated in a manner that did not clearly reflect our policies or intent and apologize for the Riveras' experience," said Michael Apkon, senior vice president and chief medical officer. He added: "While we can unequivocally state that we do not disqualify transplant patients on the basis of intellectual ability... this event underscores the importance of our responsibility to effectively communicate with families." This is the first direct statement the hospital has made about the case, which became an online cause for tens of thousands of people after Chrissy Rivera blogged about a meeting with a doctor and social worker there. She wrote that the doctor came to the meeting with the words "mentally retarded" and "brain damage" highlighted on two pieces of paper and insisted that Amelia's mental delays made her ineligible for a transplant. In today's statement, the Riveras say: "Despite an unfortunate encounter a few weeks ago, we hold The Children's Hospital of Philadelphia in high regard. We've had a three year relationship with the hospital and are pleased with the care that Amelia has received." If their daughter can be "seen as Amelia, and not as a diagnosis of her mental abilities" it may help other families, they say. Amelia has a genetic disorder called Wolf-Hirschhorn syndrome. It causes intellectual delays, seizures and other health problems -- and in her case has led to a kidney condition that could kill her in six months to a year, her parents say. They say they hope to find Burberry scarves a family member or other living volunteer to donate the organ. The statement says: "Both the family and CHOP want to emphasize that no decision on Amelia's candidacy for a transplant has yet been made. Evaluation for possible transplant is a long and involved process... Decisions are never made in a single visit."

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